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br Discussion Case reports of successful chemotherapy desens
2019-05-13

Discussion Case reports of successful chemotherapy desensitizations have been described for platinum agents, taxanes, anthracyclines, rituximab [8], and cytarabine [9], but not specifically clofarabine. For older patients with relapsed AML that are not candidates to receive anthracycline therapy,
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Significant uncertainty remains about the precise vectors th
2019-05-13

Significant uncertainty remains about the precise vectors, the plasticity of vector host-selection (ie, monkey human) and the exact location of vector exposure that results in human transmission of especially across different parts of Asia. In particular, uncertainty exists as to whether transmiss
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br In the past year migration to Europe
2019-05-13

In the past year, migration to Europe from Africa and the Middle East has reached unprecedented levels. In 2016, 181 405 migrants reached the shores of Italy and more than 5000 died trying to reach the southern coasts of Europe. Many migrants seek to escape war, poverty, persecution, or ill treatm
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A year old man was hospitalized
2019-05-13

A 36-year-old man was hospitalized following a first syncope attack while awake at night. No history of sudden death was reported in his family. On arrival, his consciousness was clear and his vital signs were stable. An electrocardiogram (ECG) showed sinus rhythm with ST-segment elevations and J wa
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The canonical or catenin dependent Wnt signaling
2019-05-10

The canonical, or β-catenin dependent, Wnt signaling pathway is critical for the regulation of osteoblast proliferation and survival [95]. Soluble inhibitors of the canonical Wnt pathway such as Dickkopf (DKK1), produced by OBL, and sclerostin, from osteocytes, play important roles in the regulation
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Therefore the patient was diagnosed
2019-05-10

Therefore, the patient was diagnosed with BIP, and steroid therapy with oral prednisolone at 40mg/day (0.5mg/kg/day) was initiated. The patient responded well to steroid therapy. After several weeks, his respiratory condition improved to Hugh–Jones class I. Since the imaging findings improved and th
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Uno de los poemas extensos
2019-05-10

Uno de los poemas extensos de Paz, que muestra con perfección esta poética de la estructuración espacial es “Vuelta”, publicado por primera vez, en forma suelta, al retorno del poeta carboxypeptidase a México en 1971, e incluido después en el poemario de mismo nombre ( 1976). En unas de las páginas
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Sierra Leone Liberia and Guinea were among the worst
2019-05-10

Sierra Leone, Liberia, and Guinea were among the worst places to be a mother before the Ebola crisis. However, substantial progress had been made in recent years in terms of maternal mortality AEG 3482 and increased access to maternal and reproductive health care, resulting in 50% of deliveries att
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br X Desde esa exigencia de
2019-05-10

X. Desde esa exigencia de una correcta hermeneusis receptora, la mecánica expositiva del misterio procederá, sin embargo, complicando esa primera alegoría que ya es el sacramento en sí y levantando, 5-aminolevulinic acid partir de la transposición o metáfora que diseña (Cristo como pan, Cristo co
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H 89 Los sectores sociales movilizados espec
2019-05-10

Los sectores sociales movilizados, específicamente las comunidades afectadas por la industria extractiva y el movimiento indígena-amazónico, no lograron articular una plataforma conjunta que ampliara sus posibilidades de exigir un trato con Gana Perú en mayor igualdad de condiciones. Mientras aidese
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In recent years the impact that
2019-05-10

In recent years, the impact that food production and consumption have had on the environment has received increasing international attention. Some food production practices and consumption behaviours are putting the environment under a great stress, contributing to climate change. The food sector ac
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Of note gender equity might continue despite the
2019-05-10

Of note, gender equity might continue despite the economic development of a society. Studies by Nussbaum and Sen have shown no direct relation between wealth and equity. Hence, some countries with high wealth, such as Saudi Arabia, also a have high degree of gender inequity, whereas others with low
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br Stephanie Topp points to the limitations of quality
2019-05-10

Stephanie Topp points to the limitations of quality measurement in Commission on High Quality Health Systems (HQSS Commission; May, 2017) that might not fit the real-world contexts of low-income and middle-income countries (LMICs). She also takes issue with a narrow set of generic indicators and
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In another study Lopez and associates found that
2019-05-10

In another study Lopez and associates found that patients with chronic heart failure receiving torsemide, a loop diuretic that inhibits the enzyme involved in the myocardial extracellular generation of collagen type I molecules (i.e., procollagen type I carboxy-terminal proteinase or PCP), had reduc
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br Case report A year old female
2019-05-10

Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (ubiquitin conjugating enzyme of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epi
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