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Breakpoint identification has been one of the most
2018-11-07
Breakpoint identification has been one of the most interesting fields in cytogenetics for investigating the phenotypic outcomes of reciprocal translocations. Several techniques had been developed to map chromosome breakpoints to the kilobase level (Chen et al., 2008; Gribble et al., 2009; Higgins et
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V SVZ derived neuroblasts exhibit
2018-11-07
V-SVZ-derived neuroblasts exhibit saltatory movement, with alternating resting and migratory phases (Wichterle et al., 1997). In the resting phase, a leading process is extended, and centrosome and Golgi apparatus move into it (swelling phase), followed by nuclear translocation and detachment of the
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br Introduction Neurofibromin Merlin NF is a tumour suppress
2018-11-07
Introduction Neurofibromin 2 (Merlin, NF2) is a tumour suppressor protein expressed during embryonic development and thereafter (Gronholm et al., 2005). In adults, significant levels of expression are found in Schwann and meningeal cells, nerve and lens (Claudio et al., 1997; Sakuda et al., 1996;
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In this study we are unable to
2018-11-07
In this study we are unable to estimate the contribution of environmental factors to schizophrenia risk. We interpret the overall higher risk in MZ twins (in all our results) as indication of the importance of genetic factors according to the classical twin model (Boomsma et al., 2002). Furthermore,
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br Materials and Methods br Results br Discussion Here
2018-11-07
Materials and Methods Results Discussion Here, we report a ddPCR-based ultrasensitive multiplex assay for the 3 common mutations of EGFR (L858R, exon 19 deletion, and T790M) in FFPE samples from NSCLC patients; this assay allows the detection of mutations in different exons with multiple pr
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rna polymerase ii The CS SVM classifier can select
2018-11-07
The CS-SVM classifier can select a small subset of stage II and III patients who can specifically benefit from 5-FU/oxaliplatin chemotherapy. Patients identified as high CS-SVM benefited significantly from chemotherapy in the training cohort (DFS, 0.001; OS, 0.0003; Fig. 5). In contrast, low CS-SVM
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br Data experimental design materials and methods
2018-11-07
Data, experimental design, materials and methods Specifications table Value of the data Data Mean peak values obtained from intact pka kinase (IC), detergent-soluble extracts (SD) and detergent-insoluble extracts (ID) associated with immature (IC2, SD2, ID2) and mature epididymal spermat
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The burner can be operated by non premixed or partially
2018-11-07
The burner can be operated by non-premixed or partially premixed mode fuel injection, and it permits adjustable settings, allowing the study of a wide range of flame types. In the present study the non-premixed combustion mode has been investigated and in Fig. 2b the air flow path is shown. Liquid f
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We have reported that retinoids both RAs and
2018-11-07
We have reported that retinoids, both RAs and retinoic phorbol myristate acetate receptor (RAR)/retinoid X receptor (RXR) analogs, are capable of enhancing macrophage cholesterol efflux, and these events involve activation of the LXR pathway [1,2]. Specifically, retinoid mediated macrophage cholest
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br Data Dataset provided in this article shows
2018-11-07
Data Dataset provided in this article shows the NMR spectra for compounds extracted from native Australian plants species Pilidiostigma glabrum, Myoporum montanum, Geijera parviflora, and Rhodomyrtus psidioides. In addition to collagen synthesis [5], additional analysis was performed to determine
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Participants were asked to sit as still as
2018-11-07
Participants were asked to sit as still as possible, to blink as little as possible, and to rest their chin on a chinrest to ensure a constant distance to the computer (57cm). Participants were instructed to ignore the sounds. EEG recording EEG data were recorded from six electrodes at standard
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br Acknowledgments br Data The dataset
2018-11-07
Acknowledgments Data The dataset of this paper provides additional information to Ref. [1]. The rear surface passivation quality in relation to the ALD Al2O3 processing parameters is reported in Figs. 1–5, the PERC cell properties are reported in Figs. 6–8 and Table 1, and the metal contact de
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Seldon has proposed that during human
2018-11-07
Seldon has proposed that during human development, white matter grows outward and expands to the overlying cortex similar to a balloon, affecting the capacity of the cortex (Seldon, 2005). The different rates of expansion in particular neutrophil elastase inhibitor regions create regional differenc
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br Adolescence developmentally meaningful indicators
2018-11-07
Adolescence (developmentally meaningful indicators) As noted several times above, general aspects of precision can be especially complex in the field due to our target population. Adolescence is a particularly long phase of development, spanning nearly a decade or more depending on whether one in
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The model is rich enough to
2018-11-07
The model is rich enough to be applied to the development of behavior, individual differences in behavior, changes in structural properties of processing systems, and data on heritability, but of course, it is highly simplified. The current model had the following limitations. First, the objective w
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