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thrombin inhibitors The naive to lineage primed transition w
2018-10-26
The naive to lineage primed transition was proposed as a gradual continuum of pluripotent states with distinct functional and transcriptional signatures and biases (Tesar, 2016). Several stem cell types with different degrees of pluripotency can be established under artificial culture conditions (Wu
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potassium channel blockers Here we report that FH iHeps deri
2018-10-26
Here, we report that FH iHeps derived from patient-specific and genetically engineered FH iPSCs can be used to test the efficacy of two well-known medications for lowering LDL-C, statins and PCSK9 antibodies, not only in vitro but also in vivo, by engrafting FH iHeps into the liver of immunodeficien
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Analysis of the data in Fig b shows
2018-10-26
Analysis of the data in Fig. 3b shows that the shape of the (222) reflection virtually does not change and corresponds to the instrumental resolution at all temperatures. The right shoulder of the (310) peak exhibits slight differences from the instrumental resolution even at high temperatures, whic
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A marginal structural model by means of additive
2018-10-26
A marginal structural model by means of additive hazard regression was thereafter applied to mortality. Additive hazard regression is a flexible model for survival analyses with the linear dependence of the model facilitating decomposition into direct, indirect, and total effects (Lange & Hansen, 20
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Migration itself may be considered a transition
2018-10-26
Migration itself may be considered a transition along the individual life-course. For example, gpr44 inhibitor from historic ‘sending’ communities (e.g. Western Mexico) may be considered a normative transition for young adults, as part of an expected trajectory of life and work in the U.S. (Massey,
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br Conclusions A premise of evolutionary thought is that
2018-10-26
Conclusions A premise of evolutionary thought is that each challenge a person faces can be of a different nature and therefore the motivations it purchase Ketorolac tromethamine salt stimulates and the actions taken to meet that challenge are also different. For example, the motivations a man
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Nevertheless other factors being controlled educational leve
2018-10-26
Nevertheless, other factors being controlled, educational level had no decisive role in the change in sexual function [27]. Consistent with the results of the present study, the findings of the study by Tan et al. showed that literate people had better sexual function than illiterate ones [28]. The
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The high prevalences of overweight
2018-10-26
The high prevalences of overweight and obesity found in the present study represent a worrying situation given the pilots were young adults and that excess weight is associated with many chronic diseases such as type II diabetes, arterial hypertension, stroke, cardiopathies, dyslipidemias and many o
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Electrochemical experiments cyclic voltammetry CV were
2018-10-26
Electrochemical experiments (cyclic voltammetry (CV)) were performed using Autolab Potentiostat/Galvanostat (Eco Chemie, Netherlands) with three-electrode cell where L/IL/ITO (laponite/Ionic Liquid/ITO) was used as working electrode, platinum (Pt) wire as the auxiliary electrode and Ag/AgCl as refer
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br Materials and method The Real Time PCR data
2018-10-26
Materials and method The Real Time PCR data have been collected by using the miniaturised platform Q3 Real Time PCR (Fig. 1). This system is based on silicon microchip able to perform Real Time PCR analysis in compact and portable way. More specifically, the platform is composed by the following
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Thermal ablation is the process by
2018-10-26
Thermal ablation is the process by which material is removed from a surface by vaporization. Since silicon is more heat resistant than biological material—silicon oxidize significantly only above 800°C—high-temperature thermal ablation presents itself as a convenient technique for regenerating biose
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Electropolymerization has been exploited for
2018-10-26
Electropolymerization has been exploited for surface imprinting in biosensors [6]. The reaction normally happens in aqueous electrolyte solution, which is favorable to retain the physiological conformation of proteins. Various polymers like pyrrole and thiophene derivatives have been used as the imp
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En un contexto econ mico y social
2018-10-26
En un contexto económico y social desfavorable como el que ha prevalecido en México desde 1980, las personas han buscado diferentes canales para mejorar sus condiciones de vida generales. Algunas de las estrategias adaptativas o incluso de supervivencia son la microempresa por emprendedores, el auto
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En suma la equidad de g nero es
2018-10-26
En suma, la equidad de género es un concepto multidimensional. Lo integran múltiples factores políticos, jurídicos, económicos, educativos y de orden familiar resultantes del juego de variables socio-culturales. De ahí la hondura de los rezagos y las dificultades de corregirlos (Frías, 2008; Dijkstr
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br Tertiarization economic determinants The residual concept
2018-10-25
Tertiarization: economic determinants The residual concept of the service sector refers back to the classification of economic sectors. Fisher (1933) broke the economy into: (i) the primary sector, encompassing agriculture and livestock farming; (ii) the secondary sector, manufacturing and; (iii)
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