Cryopreserved peripheral blood mononuclear cells PBMC

2018-10-20

Cryopreserved peripheral blood mononuclear cells (PBMC) from this patient were used for the generation of an induced pluripotent stem cell (iPSC) that harbour a “highest risk” RET mutation according to ATA guidelines, i.e. a 2753T>C missense de novo mutation at exon 16 leading to the most frequent M

Because freshly isolated hepatocytes rapidly lose their func

2018-10-20

Because freshly isolated hepatocytes rapidly lose their functions, it is a major challenge to generate fully functional hepatocytes from pluripotent stem cells. While hepatocytes derived from CPM+ LPCs expressed high levels of metabolic activity, the levels of some proteins are not as high as primar

A striking finding from this work is that

2018-10-20

A striking finding from this work is that, in serum-free conditions, chicken PGCs can survive and proliferate in the absence of stem cell factor (SCF). SCF (c-KIT ligand) is a requisite survival factor for mouse PGCs at early embryonic stages and for survival in short-term culture experiments (Gu et

Gpr or T cell death associated gene

2018-10-20

Gpr65, or T cell death-associated gene 8 (Tdag8), is a proton/acid-activated GPCR (Choi et al., 1996; Wang et al., 2004). Whereas GPR65 had not been linked to HSPC transitions, it was reported to be a pro-apoptotic factor in glucocorticoid-induced lymphocyte apoptosis (Malone et al., 2004) and to re

As a marker of cochlear supporting cells we assessed P

2018-10-20

As a marker of cochlear supporting cells, we assessed P27Kip1 localization in iCx26GJCs. P27Kip1 is a cyclin-dependent kinase inhibitor that is thought to play a role in maintaining the postmitotic state of cochlear supporting Q-VD(OMe)-OPh manufacturer such as the Deiters\' cells and outer- and inn

Hello world!

2018-07-29