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herpes simplex virus 2 ESC CMs can be subdivided into
2018-11-08
ESC-CMs can be subdivided into atrial and ventricular CMs (Burridge et al., 2012). It has been documented that the expression of the α-isoform of myosin heavy chain (α-MHC), MLC2a, and MLC1a become restricted to the atrium during murine development (Zammit et al., 2000). Here, we employed MLC2a and
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br Introduction Bone marrow derived mesenchymal stromal cell
2018-11-08
Introduction Bone marrow-derived mesenchymal stromal cell (BM-MSC)-derived osteoblasts and chondrocytes are responsible for bone and cartilage modeling/remodeling, respectively (Harada and Rodan, 2003; Wu et al., 2009). Osteoblasts are defined by lineage-specific transcription factors RUNX2 and O
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Taken together these findings indicate that basal to luminal
2018-11-08
Taken together, these findings indicate that basal-to-luminal differentiation can occur in prostate organogenesis, pathogenesis, and ex vivo assays, but rarely during normal tissue homeostasis. Thus, it has been unclear to what extent the plasticity of endogenous adult prostate basal glucocorticoid
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br Results br Discussion The Wnt signaling pathway has
2018-11-08
Results Discussion The Wnt signaling pathway has emerged as the dominant self-renewal pathway for various adult-type stem cells and is required for maintenance of embryonic as well as induced pluripotent stem cells. In the hematopoietic system, only mild increased Wnt dosages result in higher
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Although RA is sufficient to promote the
2018-11-08
Although RA is sufficient to promote the development of spermatogenic buy Biotin-tyramide from mSSCs to spermatocytes, the Sertoli cell co-culture increases further the induction efficiency. Severe apoptosis of the germ cells were observed under both the feeder-free and the co-culture conditions, i
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Active cell proliferation is key for transcription factor in
2018-11-07
Active cell proliferation is key for transcription factor-induced cell-fate change during cellular reprogramming. Because acute leukemias barely or do not proliferate in vitro, we endeavored to reprogram leukemic B cell lines as well as MLL-rearranged primary blasts induced to proliferate through xe
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Statistical correlation between religiosity spirituality
2018-11-07
Statistical correlation between religiosity, spirituality and health has been found with other health outcomes (Larson et al., 1998; Levin & Vanderpool, 1991). These include cardiovascular conditions common among older persons such as buy SBI-0206965 disease, blood pressure, cholesterol, myocardial
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Basically the treatment of AMD is based on
2018-11-07
Basically, the treatment of AMD is based on either separation such as precipitation, adsorption and filtration or any other separation or reaction process used for water and wastewater treatment. The weakness of these conventional processes includes low removal capacity, lack of selectivity and into
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En este a o M xico
2018-11-07
En este año, México es sede de la Conferencia de las Partes (cop 13) del Convenio de Diversidad Biológica, y tiene la responsabilidad de hacer visible la importancia de nuestro capital natural en la economía de nuestro país y adquirir compromisos para la Integración de la Biodiversidad (Biodiversit
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Breakpoint identification has been one of the most
2018-11-07
Breakpoint identification has been one of the most interesting fields in cytogenetics for investigating the phenotypic outcomes of reciprocal translocations. Several techniques had been developed to map chromosome breakpoints to the kilobase level (Chen et al., 2008; Gribble et al., 2009; Higgins et
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V SVZ derived neuroblasts exhibit
2018-11-07
V-SVZ-derived neuroblasts exhibit saltatory movement, with alternating resting and migratory phases (Wichterle et al., 1997). In the resting phase, a leading process is extended, and centrosome and Golgi apparatus move into it (swelling phase), followed by nuclear translocation and detachment of the
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br Introduction Neurofibromin Merlin NF is a tumour suppress
2018-11-07
Introduction Neurofibromin 2 (Merlin, NF2) is a tumour suppressor protein expressed during embryonic development and thereafter (Gronholm et al., 2005). In adults, significant levels of expression are found in Schwann and meningeal cells, nerve and lens (Claudio et al., 1997; Sakuda et al., 1996;
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In this study we are unable to
2018-11-07
In this study we are unable to estimate the contribution of environmental factors to schizophrenia risk. We interpret the overall higher risk in MZ twins (in all our results) as indication of the importance of genetic factors according to the classical twin model (Boomsma et al., 2002). Furthermore,
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br Materials and Methods br Results br Discussion Here
2018-11-07
Materials and Methods Results Discussion Here, we report a ddPCR-based ultrasensitive multiplex assay for the 3 common mutations of EGFR (L858R, exon 19 deletion, and T790M) in FFPE samples from NSCLC patients; this assay allows the detection of mutations in different exons with multiple pr
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rna polymerase ii The CS SVM classifier can select
2018-11-07
The CS-SVM classifier can select a small subset of stage II and III patients who can specifically benefit from 5-FU/oxaliplatin chemotherapy. Patients identified as high CS-SVM benefited significantly from chemotherapy in the training cohort (DFS, 0.001; OS, 0.0003; Fig. 5). In contrast, low CS-SVM
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