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Using the measured approach curves we determined
2018-11-05
Using the measured approach curves, we determined the force acting on the probe from the sample surface as the product of the cantilever spring constant k by the piezoscanner movement value dZ (this quantity is plotted on the abscissa in Fig. 2b). Next, we constructed the F(δ) dependences to find Y
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br Acknowledgment The data for this study was made
2018-11-05
Acknowledgment The data for this study was made available by another project investigating the ten-year treatment cost of breast cancer within the Norwegian Breast Cancer Screening Program. Funds from the Norwegian Research Council, Grant no. 189494, were used to establish the research database.
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We also note some limitations related to our
2018-11-05
We also note some limitations related to our data. First, the caregiving question in 2009 captured ‘sick’ and ‘disabled’ family members, however in 2013 this question was rephrased and captured ‘chronically ill’, ‘disabled’, but also ‘frail’ family members. However, it should be noted that the Engli
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In terms of social environment variables
2018-11-05
In terms of social environment variables, most studies examined gpr109a inhibitor and safety related variables, finding a positive relationship whereby participants living in socially-cohesive neighbourhoods engaged in more walking, MVPA and overall physical activity but more inconsistent findings
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br Conclusions br Outstanding Questions
2018-11-05
Conclusions Outstanding Questions Search strategy and Selection Criteria The following are the supplementary data related to this article. Authors\' Contributions Competing Interests Introduction Dendritic cells (DCs) are professional antigen presenting cells (APCs) that can effic
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SV trafficking is affected in Syn
2018-11-05
SV trafficking is affected in αSyn knocked out and transgenic mice, suggesting αSyn role in neurotransmission (Esposito et al., 2012). At short time of incubation of neurons with αSyn, the observed increase in SV mobilization and fusion may correlate to the increased calcium influx. Instead, at late
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The pooled results indicate relatively low diagnostic
2018-11-05
The pooled results indicate relatively low diagnostic sensitivity of 0.70, and specificity of 0.83, suggesting a relatively high rate of missed diagnoses (30%) and misdiagnoses (17%). Likelihood ratios >10 and the BALF CD4/CD8 ratio. In addition, diagnostic performance of the BALF CD4/CD8 ratio was
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Small cell lung cancer SCLC accounts for
2018-11-05
Small-cell lung cancer (SCLC) accounts for about 15% of all lung tumors and has a 5-year survival below 5%. While SCLC tumors are initially sensitive to chemotherapy, they invariably relapse with a resistant and deadly disease. We and others have found that, contrary to lung adenocarcinomas and squa
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br Author Contributions br Role of
2018-11-05
Author Contributions Role of the Funding Source Conflict of Interest Statement Acknowledgements This work was funded by the European Commission (FP7): “SwitchBox” (Contract HEALTH-F2-2010-259772), and co-financed by the Portuguese North Regional Operational Program (ON.2 – O Novo Norte),
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We have previously reported the CM chip that
2018-11-05
We have previously reported the CM chip that enables precise estimation of rare cell counts in blood including spiked-in cultured cancer Talabostat mesylate (Yatsushiro et al., 2010; Yamamura et al., 2012). Although the CM chip produced excellent results in a preclinical study, we considered that p
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Among the participants in our
2018-11-05
Among the 1303 participants in our study, 74% (n=964) reported xerostomia (Table 2). Xerostomia prevalence was highest among SS participants (87.4%, 95% CI: 84.8%–89.8%) followed by Sicca participants (72.4%, 95% CI: 67.4%–77.0%) and the ISS group (38.1%, 95% CI: 32.0%–44.4%). The absolute differenc
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topotecan Based on the less than expected changes in sCD and
2018-11-05
Based on the less than expected changes in sCD14 and Lp-PLA2 in both arms, in spite of virologic control, we wanted to investigate changes in lipid levels as a potential contributor to immune activation in this study. At weeks 24 and 48, there were small, statistically significant differences in inc
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Concussion is the most common type of
2018-11-05
Concussion is the most common type of traumatic ep4 injury (). Research into concussion has significantly increased in the past decade reflecting the growing recognition of repeated head-injuries in sport. Whilst the focus of the research has centred on those who have been concussed, there is also
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buy orexin agonist Disclosure br Foxp regulatory T Treg cell
2018-11-05
Disclosure Foxp3 regulatory T (Treg) buy orexin agonist are known to restrict anti-tumor immune responses and promote tumor progression (). Therapeutic utility of attenuating Treg cell function is one of the most exciting developments in the current field of tumor immunology. Temporary release f
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Sleep deprivation negatively impacts quality
2018-11-05
Sleep deprivation negatively impacts quality of life, affecting the health of the population, and is associated with increased overweight and obesity, higher risk of cardiac and metabolic diseases, as well as greater risk of accidents in the workplace and higher health costs [7–9]. Studies have high
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